Human CellExp™ CD71 / TFRC / TFR, human recombinant

Catalog number

7279-50

Size

50 μg

Price

697.00 EUR

Supplier

Biovision

Order

Details

Target

CD71 /TFRC /TFR

Background

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukemia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

Concentration

N/A

Molecular weight

This protein is fused with 6×His tag at the N-terminus, has a calculated MW of 76 kDa. The predicted N-terminus is Cys 89. DTT-reduced Protein migrates as 80-85 kDa due to glycosylation.

Synonym

CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90

Other name

CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90

NCBI gene number

7037

NCBI gene

TFRC

Gene source

Human

NCBI number

P02786

Recombinant

Yes

Source

HEK293 cells

Purification

≥92%

Tested applications

SDS-PAGE, N/A

Tested activity

N/A

Biological activity

Measured by its binding ability in a functional ELISA. Immobilized rhCD71/TFR at 10 μg/ml (100 μl/well) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/ml.

Reesults

Measured by its binding ability in a functional ELISA. Immobilized rhCD71/TFR at 10 μg/ml (100 μl/well) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/ml.

Binding ability

N/A

Unit

N/A

Storage condition

-20°C

Shipping under

Gel Pack

Physical appearance

Lyophilized

Physical properties

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

How to reconstitute

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

Aa sequence

N/A

Before use

Centrifuge the vial prior to opening.

Notes

For Research Use Only! Not to be used in humans

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Additional source

Recombinants or rec. proteins

Group

recombinants