FAAH Inhibitor, PF-622 for cell activation

Cell-permeable. A potent and irreversible FAAH (Fatty Acid Amide Hydrolase) inhibitor. Inhibits FAAH in a time-dependent manner by covalently modifying the enzyme's active site serine (IC₅₀ = 33 nM). It is highly selective for FAAH relative to other mammalian serine hydrolases.

N/A

898235-65-9

346.43

Biochemicals

N-Phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carboxamide

C₂₁H₂₂N₄O

White soild

N/A

No

Yes

≥98% by TLC

DMSO (~25 mg/ml) or Ethanol (~ 3 mg/ml)

-20°C

gel pack

36 months

Protect from light and air

cell

For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.