Compound E for cell activation
Catalog number
1949-250
Name
Compound E for cell activation
Size
250 µg
Price
191.00 EUR
Supplier
Details
Description
Cell-permeable. A potent, selective, non-transition state and non-competitive inhibitor of γ-secretase (IC₅₀ = 0.3 nM for total β-amyloid) and Notch processing. At higher concentrations (20-400 µM), only weakly affects the presenilase activity.
Peptide sequence
N/A
CAS number
209986-17-4
Molecular weight
490.5
Category
Biochemicals
Other name
(2S)-2-([(3,5-Difluorophenyl)acetyl]amino)-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide
Molecular formula
C₂₇H₂₄F₂N₄O₃
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~ 10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
