PDCD1LG2, human recombinant
Catalog number
7337-100
Name
PDCD1LG2, human recombinant
Size
50 μg
Price
349.00 EUR
Supplier
Details
Target
PDCD1LG2
Background
Programmed cell death 1 ligand 2, also known as PDCD1LG2, is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Recombinant human PDCD1LG2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Concentration
1 mg/ml
Molecular weight
22.8 kDa (204 aa, 20-200 aa + His Tag), confirmed by MALDI-TOF. (MW on SDS-PAGE shifts up)
Synonym
Programmed cell death 1 ligand 2, B7DC, bA574F11.2, Btdc, CD273, PD-L2, PDCD1L2, PDL2
Other name
Programmed cell death 1 ligand 2, B7DC, bA574F11.2, Btdc, CD273, PD-L2, PDCD1L2, PDL2
NCBI gene number
80380
NCBI gene
PDCD1LG2
Gene source
Human
NCBI number
Q9BQ51
Recombinant
Yes
Source
E. coli
Purification
≥90%
Tested applications
SDS-PAGE, N/A
Level of endotoxin
< 1.0 EU per 1 microgram of protein
Tested activity
N/A
Biological activity
N/A
Reesults
N/A
Binding ability
N/A
Unit
N/A
Storage condition
-80°C
Shipping under
Dry Ice
Physical appearance
Liquid
Physical properties
1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, and 0.4 M Urea.
How to reconstitute
N/A
Aa sequence
MGSSHHHHHH SSGLVPRGSH MGSLFTVTVP KELYIIEHGS NVTLECNFDT GSHVNLGAIT ASLQKVENDT SPHRERATLL EEQLPLGKAS FHIPQVQVRD EGQYQCIIIY GVAWDYKYLT LKVKASYRKI NTHILKVPET DEVELTCQAT GYPLAEVSWP NVSVPANTSH SRTPEGLYQV TSVLRLKPPP GRNFSCVFWN THVR
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants