IWP-2 for cell activation
Catalog number
1962-25
Name
IWP-2 for cell activation
Size
25 mg
Price
616.00 EUR
Supplier
Details
Description
Cell-permeable. Acts as an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC₅₀ = 27 nM) by inhibition of the O-acyltransferase Porcn. Porcn is a member of the membrane-bound O-acyltransferase (MBOAT) family, which adds a palmitoyl group to Wnt proteins that is essential to their signaling ability and is required for Wnt secretion.
Peptide sequence
N/A
CAS number
686770-61-6
Molecular weight
466.6
Category
Biochemicals
Other name
N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Molecular formula
C₂₂H₁₈N₄O₃S₃
Physical appearance
Beige solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by TLC
Reconstitute instructions
DMSO (~5 mg/ml with warming)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
48 months
Storage instructions
Protect from light and air
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
