DPP IV Inhibitor, K 579 for cell activation

Cell-permeable. A potent, slow binding dipeptidyl peptidase IV inhibitor with IC₅₀ values of 3, 5, 8, and 8 nM for rat, canine, human and monkey enzymes respectively. Acts as a long-acting hypoglycemic agent.

N/A

440100-64-1

328.41

Biochemicals

(2S)-1-[[[4-Methyl-1-(2-pyrimidinyl)-4-piperidinyl]amino]acetyl]-2-pyrrolidinecarbonitrile

C₁₇H₂₄N₆O

Light brown solid

N/A

No

Yes

≥98% by HPLC

DMSO (~100 mM) or EtOH (~ 20 mM) or 1 eq. HCl (50 mM)

-20°C

gel pack

48 months

Protect from light and air

cell

For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.