IGF-BP6, human recombinant
Catalog number
7350-20
Name
IGF-BP6, human recombinant
Size
20 μg
Price
445.00 EUR
Supplier
Details
Synonyms
insln-like growth factor-binding protein 6, IBP6
Alternates names
insln-like growth factor-binding protein 6, IBP6
Taglines
Regulates the growth promoting effects of the IGFs on cell culture
Biomolecule/Target
IGFBP6
NCBI Gene ID #.
3489
NCBI Gene Symbol
IGFBP6
Gene Source
Human
Accession #
P24592
Recombinant
Yes
Source
E. coli
Purity
N/A
Endotoxin Level
N/A
Activity (Specifications/test method)
N/A
Biological activity
N/A
Results
N/A
Molecular Weight
25 kDa (236 aa, 28-240 aa + His Tag), confirmed by MALDI-TOF.
Storage Temp.
-80°C
Shipping
Dry Ice
Shelf Life
1 year
Concentration
0.5 mg/ml
Appearance
Liquid
Physical form description
0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 1 mM DTT and 20% glycerol.
Reconstitution Instructions
N/A
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description
IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.
Additional source
Recombinants or rec. proteins
Group
recombinants
