MMP-9 Inhibitor for cell activation

Cell-permeable. A potent, selective, and reversible MMP-9 Inhibitor (IC₅₀ = 5 nM). Inhibits MMP-1 (IC₅₀ = 1.05 µM) and MMP-13 (IC₅₀ = 113 nM) only at much higher concentrations.

N/A

1177749-58-4

511.63

Biochemicals

2-(N-benzyl-4-methoxyphenylsulfonamido)-5-((diethylamino)methyl)-N-hydroxy-3-methylbenzamide

C₂₇H₃₃N₃O₅S

Off-white solid

N/A

No

Yes

≥95% by HPLC

DMSO

-20°C

gel pack

60 months

Protect from light and air

cell

For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.