Cathepsin G Inhibitor for cell activation

A potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (IC₅₀ = 53 nM and Ki = 63 nM). Acts as a weak inhibitor of chymotrypsin (Ki = 1.5 µM), thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC₅₀ > 100 µM).

N/A

429676-93-7

620.63

Biochemicals

C₃₆H₃₃N₂O₆P

White solid

N/A

No

No

≥98% by HPLC

DMSO

-20°C

gel pack

60 months

Protect from light and mositure

cell

CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.

For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.