Itraconazole for cell activation
Catalog number
1987-500
Name
Itraconazole for cell activation
Size
500 mg
Price
420.00 EUR
Supplier
Details
Description
A synthetic broad-spectrum triazole antifungal agent with the mode of action being through Inhibition of cytochrome P450 dependent enzymes including 14α-demethylase. Recently, it has been shown that Itraconazole inhibits Hedgehog (Hh) signaling pathway activity (IC50 = 0.8 µM) as well as blocks the VEGFR2 glycosylation, trafficking, and signaling in endothelial cells.
Peptide sequence
N/A
CAS number
84625-61-6
Molecular weight
705.63
Category
Biochemicals
Other name
(2R,4S)-rel-1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one; Oriconazole, R51211, Sporanox
Molecular formula
C₃₅H₃₈Cl₂N₈O₄
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
No
Purification
≥97%
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
60 months
Storage instructions
Protect from light and air
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
