Masitinib for cell activation

Cell-permeable. A protein tyrosine kinase (PTK) inhibitor.  targeting KIT that is active, orally bioavailable in vivo, and has low toxicity. Masitinib also potently inhibited recombinant PDGFR and the intracellular kinase Lyn, and to a lesser extent, fibroblast growth factor receptor 3. In contrast, masitinib demonstrated weak inhibition of ABL and c-Fms and was inactive against a variety of other tyrosine and serine/threonine kinases.

N/A

790299-79-5

498.64

Biochemicals

AB-1010

C₂₈H₃₀N₆OS

Off-white solid

N/A

No

Yes

≥99% by HPLC

DMSO (>100 mg/ml) or EtOH (4 mg/ml)

-20°C

gel pack

24months

Protect from air and light

cell

For cells, cell lines and tissues in culture till half confluency.