RO-3306 for cell activation
Catalog number
2039-5
Name
RO-3306 for cell activation
Size
5 mg
Price
338.00 EUR
Supplier
Details
Description
Cell-permeable. A selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Arrests cell cycle at G1, S, and G2/M and induces apoptosis in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines, and suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387.
Peptide sequence
N/A
CAS number
872573-93-8
Molecular weight
351.45
Category
Biochemicals
Other name
(5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one
Molecular formula
C₁₈H₁₃N₃OS₂
Physical appearance
Brown solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by NMR
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
