PKC412 for cell activation
Catalog number
2052-5
Name
PKC412 for cell activation
Size
5 mg
Price
599.00 EUR
Supplier
Details
Description
Cell-permeable. A derivative of Staurosporine (Cat. No. 1048) that inhibits a variety of serine/threonine and tyrosine kinases including protein kinase C (PKC) IC₅₀ = 50 nM), cyclic AMP-dependent protein kinase (PKA) (IC₅₀ = 2.4 µM), S6 kinase (IC₅₀ = 5.0 µM), and EGFR (IC₅₀ = 3.0 µM). PKC412 reverses the efflux function of the multidrug resistance (MDR)-1 gene product, P-glycoprotein (P-gp).
Peptide sequence
N/A
CAS number
120685-11-2
Molecular weight
570.64
Category
Biochemicals
Other name
4'-N-Benzoyl Staurosporine; CGP-41251; Midostaurin
Molecular formula
C₃₅H₃₀N₄O₄
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99% by HPLC
Reconstitute instructions
DMSO (~ 10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
