TAPI-0 for cell activation
Catalog number
2067-1
Name
TAPI-0 for cell activation
Size
1 mg
Price
387.00 EUR
Supplier
Details
Description
Inhibitor of TNF-α processing (IC₅₀ = 100 nM). Inhibits TACE (ADAM17) and other metalloproteases with Ki (nM) values of 8.8, 17, 6, 68, 0.5 and 0.2 for TACE, MDC9 (ADAM9), MMP-1, MMP-3, MMP-9 and MMP-13, respectively.
Peptide sequence
N/A
CAS number
143457-40-3
Molecular weight
456.55
Category
Biochemicals
Other name
N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-naphthylalanyl-L-alanine amide; TNF protease inhibitor-0; C1
Molecular formula
C₂₄H₃₂N₄O₅
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
No
Purification
≥95% by HPLC
Reconstitute instructions
DMSO (~ 5 mg/ml) or acetic acid (~ 5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
