Garcinol for cell activation

Catalog number
2088-5
Name
Garcinol for cell activation
Size
5 mg
Price
137.00 EUR
Supplier

Details

Description
Garcinol is a polyisoprenylated benzophenone derivative isolated from Garcinia indica. It is a potent inhibitor of histone acetyltransferases (HATs) p300 (IC50 = 7 µM) and PCAF (IC50 = 5 µM) both in vitro and in vivo. HAT activity-dependent chromatin transcription was inhibited by garcinol, but it had no effect on naked DNA transcription. Moreover, it induces apoptosis in several types of cancer cells and has anti-inflammatory actions. Garcinol promotes neurogenesis and ex vivo expansion of human hematopoietic stem cells.
Peptide sequence
N/A
CAS number
78824-30-3
Molecular weight
602.80
Category
Biochemicals
Other name
Camboginol
Molecular formula
C₃₈H₅₀O₆
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥95% by TLC
Reconstitute instructions
DMSO (25 mg/ml) or EtOH (25 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.