Nodularin for cell activation
Catalog number
2094-50
Name
Nodularin for cell activation
Size
50 μg
Price
126.00 EUR
Supplier
Details
Description
Nodularin is a hepatotoxic monocylic pentapeptide produced by cyanobacterium Nodularia spumigena. It is a potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), exhibiting IC₅₀ values of 1.8 and 0.026 nM, respectively. It inhibits PP2B only at higher concentrations ( IC₅₀ = 1.8 µM).
Peptide sequence
N/A
CAS number
118399-22-7
Molecular weight
824.96
Category
Biochemicals
Other name
Cyclo[3S-amino-9S-methoxy-2S,6E,8S-trimethyl-10-phenyl-4,6- decadienoyl-D-γ-glutamyl-(2Z)-2-(methylamino)-2-butenoyl-(3S)- 3-methyl-D-β-aspartyl-L-arginyl]
Molecular formula
C₄₁H₆₀N₈O₁₀
Physical appearance
Liquid
Supplied with
In Ethanol
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥95%
Reconstitute instructions
N/A
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
