Nexturastat A for cell activation

Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC₅₀ = 5.02 ± 0.60 nM). Displays 600-, 1380-, 1330-, 1870-, -2330, -888, -190, -1340, -1510, and -1020-fold selectivities over HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, HDAC9, HDAC10, and HDAC11, respectively. Nexturastat A also displays antiproliferative effects against melanoma cells.

N/A

1403783-31-2

341.4

Biochemicals

4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide

C₁₉H₂₃N₃O₃

Off-white solid

N/A

N/A

Yes

≥98% by HPLC

DMSO

-20°C

gel pack

24months

Protect from air and light

cell

For cells, cell lines and tissues in culture till half confluency.