Nexturastat A for cell activation

Catalog number
2098-1
Name
Nexturastat A for cell activation
Size
1 mg
Price
191.00 EUR
Supplier

Details

Description
Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC₅₀ = 5.02 ± 0.60 nM). Displays 600-, 1380-, 1330-, 1870-, -2330, -888, -190, -1340, -1510, and -1020-fold selectivities over HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, HDAC9, HDAC10, and HDAC11, respectively. Nexturastat A also displays antiproliferative effects against melanoma cells.
Peptide sequence
N/A
CAS number
1403783-31-2
Molecular weight
341.4
Category
Biochemicals
Other name
4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide
Molecular formula
C₁₉H₂₃N₃O₃
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.