Active Caspase-1, rat recombinant

Catalog number
7524-25
Name
Active Caspase-1, rat recombinant
Size
25 units
Price
415.00 EUR
Supplier
Biovision
Order

Details

Synonyms
Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, IL-1BC, p45.
Alternates names
Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, IL-1BC, p45.
Taglines
A cysteine protease involved in apoptosis
Biomolecule/Target
Caspase-1
NCBI Gene ID #.
N/A
NCBI Gene Symbol
Casp1
Gene Source
Rat
Accession #
P43527
Recombinant
Yes
Source
E. coli
Purity
N/A
Endotoxin Level
N/A
Activity (Specifications/test method)
N/A
Biological activity
The caspase-1 is routinely tested at BioVision for its ability to cleave these two substrates Ac-YVAD-pNA (Cat. #1104-200) or Ac-YVAD-AFC (1103-200).
Results
>3000 units/mg
Molecular Weight
~ 34.6 KDa
Storage Temp.
-20°C
Shipping
Gel Pack
Shelf Life
1 year
Concentration
N/A
Appearance
Semi-Dry
Physical form description
Semi-Dry
Reconstitution Instructions
Reconstitute to 1 unit per μl in PBS containing 15% glycerol.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name
Rattus norvegicus
Additional source
Recombinants or rec. proteins
Group
recombinants