3,3'-Diindolylmethane for cell activation

Diindolylmethane (DIM) is a natural compound present in food plants of the Brassica genus, including broccoli, cabbage, Brussels sprouts, cauliflower and kale. Displays antitumor and proapoptotic properties in animal and in in vitro models of cancer. Also acts a selective and potent inhibitor of cancer stem cells, and HDAC activity in prostate cancer cells. Recently, it has been shown that DIM induces apoptosis in ovarian cancer cells by inhibiting JAK2/STAT3.

N/A

1968-05-4

246.31

Biochemicals

3,3’-Methylenediindole; DIM

C₁₇H₁₄N₂

White to Off-white Solid

N/A

No

Yes

≥98% by HPLC

DMSO (25 mg/ml)

-20°C

gel pack

24months

Protect from air and light

cell

For cells, cell lines and tissues in culture till half confluency.