α-Galactosylceramide for cell activation
Catalog number
2152-250
Name
α-Galactosylceramide for cell activation
Size
250 µg
Price
208.00 EUR
Supplier
Details
Description
α-GalCer is a specific ligand for human and mouse natural killer T (NKT) cells; exhibits potent anti-tumor activity with murine in vivo experiments including subcutaneous implanted model and metastatic models in the liver and lung. KRN7000 has been reported to show various immunological effects in infectious diseases, autoimmune disease and graft verse host disease in mice.
Peptide sequence
N/A
CAS number
158021-47-7
Molecular weight
858.32
Category
Biochemicals
Other name
alpha-Galactosylceramide; αGalCer; KRN7000; (2S,3S,4R)-1-O-(α-D-galactosyl)-N-hexacosanoyl-2-amino- 1,3,4-octadecanetriol
Molecular formula
C₅₀H₉₉NO₉
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
No
Purification
≥96% by NMR
Reconstitute instructions
For In vivo assay: Use 5.6% sucrose, 0.75% L-histidine and 0.5% Tween20 with heating at 60-80 ̊C. For In vitro assay: should be dissolved in DMSO at the concentration of 1 mg/ml with heating at 60-80 ̊C . The solution of 1mg/ml in DMSO can be diluted by PBS.
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
