Ebselen for cell activation

Catalog number
2169-5
Name
Ebselen for cell activation
Size
5 mg
Price
115.00 EUR
Supplier

Details

Description
An organo-selenium compound that displays potent antioxidant properties. Acts as a glutathione peroxidase (GPX) mimic as well as being an excellent scavenger of peroxynitrite. The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase (COX) and lipoxygenases at micromolar concentrations. Also acts as a histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1B protein with an IC₅₀ of 5.17 µM.
Peptide sequence
N/A
CAS number
60940-34-3
Molecular weight
274.18
Category
Biochemicals
Other name
2-Phenyl-1,2-benzisoselenazol-3-(2H)-one
Molecular formula
C₁₃H₉NOSe
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99%
Reconstitute instructions
DMSO (~ 5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.