Human CellExp™ Netrin-1, human recombinant

Catalog number
7575-10
Name
Human CellExp™ Netrin-1, human recombinant
Size
10 μg
Price
420.00 EUR
Supplier

Details

Target
Netrin-1
Background
Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also Involved in tumorigenesis by regulating apoptosis.
Concentration
N/A
Molecular weight
~80.0 kDa. Human netrin-1 (aa 25-604) is fused at the C-terminus to a FLAG®-tag.
Synonym
NTN1
Other name
NTN1
NCBI gene number
9423
NCBI gene
NTN1
Gene source
Human
NCBI number
O95631
Recombinant
Yes
Source
HEK293 cells
Purification
≥95%
Tested applications
SDS-PAGE, N/A
Tested activity
Induces axon outgrowth.
Biological activity
Induces axon outgrowth.
Reesults
Induces axon outgrowth.
Binding ability
N/A
Unit
N/A
Storage condition
-20°C
Shipping under
Gel Pack
Physical appearance
Lyophilized
Physical properties
Lyophilized in PBS with trehalose and Brij 35.
How to reconstitute
Reconstitute with 100 μl sterile distilled water.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants