Lithocholic acid for cell activation
Catalog number
2187-1G
Name
Lithocholic acid for cell activation
Size
1 g
Price
115.00 EUR
Supplier
Details
Description
Lithocholic acid (LCA) is a hydrophobic secondary bile acid that is primarily formed in the intestine by the bacterial 7-α dehydroxylation of chenodeoxycholic acid. Acts as a detergent to solubilize fats for absorption. Known to display both carcinogenic and apoptotic activities. Also binds to the p53 binding sites of both MDM2 and MDM4 with a five-fold preference for MDM4.
Peptide sequence
N/A
CAS number
434-13-9
Molecular weight
376.57
Category
Biochemicals
Other name
3α-Hydroxy-5β-cholan-24-oic acid, 3α-Hydroxy-5β-cholanic acid, 5β-Cholan-24-oic acid-3α-ol; LCA
Molecular formula
C₂₄H₄₀O₃
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
No
Purification
≥97% by TLC
Reconstitute instructions
DMSO or EtOH
Storage condition
RT
Shipping condition
RT
Maximum time for storage
24months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
