Valinomycin for cell activation
Catalog number
2238-10
Name
Valinomycin for cell activation
Size
10 mg
Price
121.00 EUR
Supplier
Details
Description
A highly selective K⁺- ionophore. It binds potassium ions (K⁺) and facilitates their transfer across lipid bilayers. Inhibits Ca²⁺-ATPase activity and promotes cell death by mitochondrial swelling and autophagic processes, but not apoptosis. Antagonizes endothelin-induced vasoconstriction (IC₅₀ = 0.3 µM).
Peptide sequence
N/A
CAS number
2001-95-8
Molecular weight
1111.32
Category
Biochemicals
Other name
Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl)
Molecular formula
C₅₄H₉₀N₆O₁₈
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99%
Reconstitute instructions
DMSO (25 mM) or EtOH (25 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
