WRD9 bromodomain 2 (1310-1426 aa) (GST-tagged), Human recombinant

BRWD1

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. WDR9 possesses two bromodomain motifs and eight WD repeats. WDR9 is also known to interact with BRG1 (SMARCA4). This product contains the bromodomain 2 region of WDR9.

N/A

40.3 kDa (1310-1426 aa + GST Tag)

WRD9 bromodomain 2 (1310-1426 aa) (GST-tagged), Human recombinant

BRD and WD repeat-containing protein 1; WD repeat-containing protein 9

54014

BRWD1

Human

Q9NSI6

Yes

E. coli

≥85%

SDS-PAGE, HPLC

N/A

N/A

N/A

N/A

N/A

N/A

-80°C

dry ice

Liquid

50 mM Tris, pH 7.5, containing 500 mM sodium chloride, 5% glycerol, and 5 mM β-mercaptoethanol.

N/A

N/A

Centrifuge the vial prior to opening.

For Research Use Only! Not to be used in humans

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Recombinants or rec. proteins

recombinants