MEK-162 for cell activation
Catalog number
2254-5
Name
MEK-162 for cell activation
Size
5 mg
Price
121.00 EUR
Supplier
Details
Description
Cell-permeable. A potent, non-ATP competitive inhibitor of MEK1/2 (IC₅₀ = 12 nM) and cellular pERK (IC₅₀ = 11 nM). Selective against a panel of other 220 kinases (displays no activity even at 10 µM).
Peptide sequence
N/A
CAS number
606143-89-9
Molecular weight
441.23
Category
Biochemicals
Other name
5-[(4-Bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide; methyl-1H-benzimidazole-6-carboxamide; ARRY
Molecular formula
C₁₇H₁₅BrF₂N₄O₃
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~100 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
