Xanthohumol for cell activation
Catalog number
2258-5
Name
Xanthohumol for cell activation
Size
5 mg
Price
142.00 EUR
Supplier
Details
Description
Cell-permeable. A bioactive flavonoid antioxidant found in the flowering hops plant. Binds to the N-terminal domain of valosin-containing protein (VCP), an essential protein for autophagosome maturation. Xanthohumol inhibits the function of VCP thereby impairing autophagosome maturation and resulting in accumulation of the microtubule-associated protein 1 light chain 3-II (LC3-II). Impairs prostate cancer cell growth and proliferation.
Peptide sequence
No
CAS number
6754-58-1
Molecular weight
354.40
Category
Biochemicals
Other name
(2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)- 2-propen-1-one
Molecular formula
C₂₁H₂₂O₅
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by TLC
Reconstitute instructions
DMSO (~35 mg/ml) or EtOH (~35 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from light and mositure
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
