Torin 2 for cell activation
Catalog number
2274-5
Name
Torin 2 for cell activation
Size
5 mg
Price
175.00 EUR
Supplier
Details
Description
A potent, selective and ATP-competitive mTOR inhibitor (IC₅₀ = 2.1 nM for mTORC1). Torin 2 displays 800-fold selectivity for mTOR over PI3K (cellular EC₅₀ values of 0.25 nM and 200 nM, respectively) and exhibits 100-fold binding selectivity relative to 440 other protein kinases.
Peptide sequence
N/A
CAS number
1223001-51-1
Molecular weight
432.40
Category
Biochemicals
Other name
9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-benzo[h]-1,6-naphthyridin-2(1H)-one
Molecular formula
C₂₄H₁₅F₃N₄O
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~8 mg/ml)
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
