Atorvastatin for cell activation
Catalog number
2278-50
Name
Atorvastatin for cell activation
Size
50 mg
Price
371.00 EUR
Supplier
Details
Description
A cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase (IC₅₀ = 154 nM) a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. In addition to inhibiting cholesterol synthesis, atorvastatin reduces the production of low-density lipoprotein (LDL).
Peptide sequence
N/A
CAS number
134523-00-5
Molecular weight
558.64
Category
Biochemicals
Other name
2-(4-fluorophenyl)-βR,δR-dihydroxy-5-(1-methylethyl)-3-phenyl- 4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid
Molecular formula
C₃₃H₃₅FN₂O₅
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO (~15 mg/ml) or EtOH (~0.5 mg/ml)
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
