GSK461364 for cell activation
Catalog number
2287-25
Name
GSK461364 for cell activation
Size
25 mg
Price
893.00 EUR
Supplier
Details
Description
A potent, selective and ATP-competitive inhibitor of Polo Like Kinase 1 (PLK1) (Ki = 2 nM). Displays >100-fold selectivity for PLK1 over PLK2 and PLK3. Shows anti-proliferative activity against several tumor cell lines.
Peptide sequence
No
CAS number
929095-18-1
Molecular weight
543.60
Category
Biochemicals
Other name
5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-((R)-1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide
Molecular formula
C₂₇H₂₈F₃N₅O₂S
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~10 mg/ml)
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
