ErbB4/HER4 (His Tagged), Human Recombinant

Catalog number

7773-5

Size

5 μg

Price

345.00 EUR

Supplier

Biovision

Order

Details

Synonyms

ErbB4/HER4 (His Tagged), Human Recombinant

Alternates names

HER4, MGC138404, p180erbB4, ERBB4

Taglines

Plays important roles in differentiation, development and certain carcinomas

Biomolecule/Target

ERBB4

NCBI Gene ID #.

2066

NCBI Gene Symbol

ERBB4

Gene Source

Human

Accession #

Q15303

Recombinant

Yes

Source

Human

Purity

N/A

Endotoxin Level

< 1.0 EU per μg of the protein as determined by the LAL method.

Activity (Specifications/test method)

N/A

Biological activity

1. Measured by its ability to bind biotinylated human Fc-NRG1 (isoform Beta 1) in a functional ELISA. 2. Measured by its ability to bind with biotinylated human NRG1 (isoform Beta 1) in a functional ELISA. 3. Measured by its ability to bind with biotinylated human NRG1 (aa 2-246)-Fc in a functional ELISA. 4. Measured by its ability to bind with biotinylated human NRG1 (aa 20-241)-His in a functional ELISA.

Results

N/A

Molecular Weight

The recombinant human ErbB4/Fc is a disulfide-linked homodimeric protein after proteolytic removal of the signal peptide. The reduced monomer consists of 871 amino acids with a predicted molecular mass of 97.5 kDa. As a result of glycosylation, the rh ErbB4/Fc monomer migrates as approximately 125-135 kDa band in SDS-PAGE under reducing conditions.

Storage Temp.

-80°C

Shipping

dry ice

Shelf Life

1 year

Concentration

N/A

Appearance

Lyophilized

Physical form description

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Reconstitution Instructions

N/A

Handling

Centrifuge the vial prior to opening.

Usage

For Research Use Only! Not to be used in humans

Conjugation

histidine

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Additional source

Recombinants or rec. proteins

Group

recombinants