ROCK Inhibitor (Rockout) for cell activation

Catalog number
2342-25
Name
ROCK Inhibitor (Rockout) for cell activation
Size
25 mg
Price
295.00 EUR
Supplier

Details

Description
A cell-permeable, ATP-competitive inhibitor of Rho kinase (ROCK) activity in vitro (IC₅₀ = 25 µM). Inhibits blebbing o trypsinized Swiss3T3 and M2 cells.
Peptide sequence
N/A
CAS number
7272-84-6
Molecular weight
194.23
Category
Biochemicals
Other name
3-(4-Pyridyl)-1H-indole
Molecular formula
C₁₃H₁₀N₂
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (25 mg/ml)
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.