EZSolution™ Torin 1 for cell activation

Catalog number
2353-5
Name
EZSolution™ Torin 1 for cell activation
Size
5 mg
Price
197.00 EUR
Supplier

Details

Description
A potent, selective and ATP-competitive mTOR inhibitor, with IC₅₀ values of 2 and 10 nM for mTORC1 and mTORC2 respectively; Torin1 displays 1000-fold selectivity for mTOR over PI3K (EC₅₀ = 1800 nM) and exhibits 100-fold binding selectivity relative to 450 other protein kinases.
Peptide sequence
N/A
CAS number
1222998-36-8
Molecular weight
607.62
Category
Biochemicals
Other name
1-[4-[4-(1-Oxopropyl)-1-piperazinyl­]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benz­o[h]-1,6-naphthyridin-2(1H)-one
Molecular formula
C₃₅H₂₈F₃N₅O₂
Physical appearance
Liquid
Supplied with
A 10 mM solution in DMSO
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
N/A
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
12 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.