Borrelidin for cell activation
Catalog number
2367-1000
Name
Borrelidin for cell activation
Size
1 mg
Price
512.00 EUR
Supplier
Details
Description
A macrolide antibiotic isolated from Streptomyces sp. An antiangiogenic (IC₅₀ = 0.8 nM) agent. Bacterial and eukaryal threonyl-tRNA synthetase (THrRS) inhibitor. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Also acts as a CDK inhibitor.
Peptide sequence
N/A
CAS number
7184-60-3
Molecular weight
489.64
Category
Biochemicals
Other name
Treponemycin; U 78548; C2989
Molecular formula
C₂₈H₄₃NO₆
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~10 mg/ml)
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
