Fumagillin for cell activation
Catalog number
2368-1
Name
Fumagillin for cell activation
Size
1 mg
Price
262.00 EUR
Supplier
Details
Description
Fumagillin is a meroterpenoid antibiotic isolated from Aspergillus fumigatus. An anticancer, antimicrobial, antimalarial and amoebicidal compound. Potent, selective and covalent inhibitor of methionine aminopeptidase-2 (MetAP2). Anti-angiogenic by impairing the growth of endothelial cells and altering gene expression. Inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo.
Peptide sequence
N/A
CAS number
23110-15-8
Molecular weight
458.54
Category
Biochemicals
Other name
Amebacilin; Fugilin; Fumidil; Fumadil B; NSC9168; U5762
Molecular formula
C₂₆H₃₄O₇
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by NMR
Reconstitute instructions
Ethanol (~ 1 mg/ml)
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.