Gossypin for cell activation
Catalog number
2374-250
Name
Gossypin for cell activation
Size
250 mg
Price
371.00 EUR
Supplier
Details
Description
A glucoside occurring in cotton and Hubiscus flowers that acts as a potent antimelanoma agent. Gossypin inhibits human melanoma cell proliferation, in vitro, in melanoma cell lines that harbors both BRAF-V600E kinase and CDK4 as well as in cells with BRAF wild-type allele. Gossypin inhibits the kinase activities of BRAF-V600E and CDK4, in vitro, possibly through direct binding with these kinases.
Peptide sequence
N/A
CAS number
652-78-8
Molecular weight
480.38
Category
Biochemicals
Other name
3,3',4',5,7,8-Hexahydroxyflavone-8-glucoside
Molecular formula
C₂₁H₂₀O₁₃
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from light and air
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
