(-)-JQ1 for cell activation
Catalog number
2384-1
Name
(-)-JQ1 for cell activation
Size
1 mg
Price
186.00 EUR
Supplier
Details
Description
Cell-permeable. A useful negative control for the BET bromodomain inhibitor (+)-JQ1 (Cat.No.2070). (−)-JQ1 enantiomer has no appreciable affinity to BET bromodomains, whereas enantiomerically pure (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~ 50 and 90 nM, respectively.
Peptide sequence
N/A
CAS number
1268524-71-5
Molecular weight
456.99
Category
Biochemicals
Other name
t-Butyl-2-((6R)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
Molecular formula
C₂₃H₂₅ClN₄O₂S
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~10 mg/ml)
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from light and air
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
