MMP-13 inhibitor for cell activation

CL-82198 is a selective inhibitor of MMP-13 (IC₅₀ = 10 µM). It displays no activity against MMP-1, MMP-9 or TACE.

N/A

307002-71-7

302.37

Biochemicals

N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide; CL-82198

C₁₇H₂₂N₂O₃

Off-white solid

N/A

No

Yes

≥98% by TLC

DMSO (~10 mg/ml)

-20 ̊C

gel pack

36 months

Protect from light and air

cell

For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.