(±)-Blebbistatin for cell activation
Catalog number
2405-25
Name
(±)-Blebbistatin for cell activation
Size
25 mg
Price
556.00 EUR
Supplier
Details
Description
Cell-permeable. A selective inhibitor of non-muscle myosin II ATPases. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC₅₀ = 0.5-5.0 μM), while weakly inhibiting smooth muscle myosin (IC₅₀ = 80 μM). Through these effects, blebbistatin reversibly blocks apoptosis-related bleb formation, directed cell migration and cytokinesis in vertebrate cells.
Peptide sequence
N/A
CAS number
674289-55-5
Molecular weight
292.34
Category
Biochemicals
Other name
(±)-1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one
Molecular formula
C₁₈H₁₆N₂O₂
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~25 mg/ml)
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from light and air
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
