Phytosphingosine for cell activation

Phytosphingosine is a phospholipid structurally similar to Sphingosine (Cat. No. 2425). The physiological roles of phytosphingosine are largely unknown. Phytosphingosine induces apoptosis in human T-cell lymphoma and non-small cell lung cancer cells, and induces caspase-independent cytochrome c release from mitochondria. In the presence of caspase inhibitors, phytosphingosine-induced apoptosis is almost completely suppressed, suggesting that phytosphingosine-induced apoptosis is largely dependent on caspase activities.

N/A

554-62-1

317.51

Biochemicals

4-Hydroxysphinganine, D-Ribo-1,3,4-trihydroxy-2-aminooctadecane, D-Ribo-2-aminooctadecane-1,3,4-triol, PHS

C₁₈H₃₉NO₃

White solid

N/A

No

Yes

≥98% by TLC

EtOH (~ 2 mg/ml)

-20 ̊C

gel pack

36 months

Protect from air and moisture

cell

For cells, cell lines and tissues in culture till half confluency.