Human CellExp™ TIM3/HAVR2 Protein, Human Recombinant

Catalog number

P1002-20

Size

20 μg

Price

300.00 EUR

Supplier

Biovision

Order

Details

Target

TIM3/HAVR2

Background

Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.

Concentration

N/A

Molecular weight

This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 20.7 kDa. The predicted N-terminus is Ser 22. DTT-reduced Protein migrates as 28-48 kDa due to glycosylation.

Synonym

Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3

Other name

Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3

NCBI gene number

84868

NCBI gene

HAVCR2

Gene source

Human

NCBI number

Q8TDQ0

Recombinant

Yes

Source

HEK 293 cells

Purification

≥95%

Tested applications

SDS-PAGE, N/A

Tested activity

N/A

Biological activity

N/A

Reesults

N/A

Binding ability

N/A

Unit

N/A

Storage condition

4°C in lyophilized state

Shipping under

Gel pack

Physical appearance

Dry powder

Physical properties

Lyophilized powder

How to reconstitute

Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH7.4) to a stock solution of 400 µg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storage.

Aa sequence

Ser 22 - Arg 220

Before use

Centrifuge the vial prior to opening.

Notes

For Research Use Only! Not to be used in humans

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Additional source

Recombinants or rec. proteins

Group

recombinants