Enfuvirtide Acetate for cell activation

Catalog number
2440-1
Name
Enfuvirtide Acetate for cell activation
Size
1 mg
Price
153.00 EUR
Supplier

Details

Description
Enfuvirtide is an antiretroviral drug used in combination therapy for the treatment of HIV-1/AIDS. It binds to the first heptad-repeat (HR1) in the gp41 subunit of the viral envelope glycoprotein and prevents the conformational changes required for the fusion of viral and cellular membranes. It works by disrupting the HIV-1 molecular machinery at the final stage of fusion with the target cell, preventing uninfected cells from becoming infected.
Peptide sequence
Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2. CH3CO2H
CAS number
914454-00-5
Molecular weight
4552.62
Category
Biochemicals
Other name
Fuzeon; T20; Pentafuside
Molecular formula
C₂₀₆H₃₀₅N₅₁O₆₆
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
Yes
Is it cell-permeable?
No
Purification
≥98%
Reconstitute instructions
H₂O (~ 100 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.