RITA for cell activation
Catalog number
2469-25
Name
RITA for cell activation
Size
25 mg
Price
458.00 EUR
Supplier
Details
Description
RITA (reactivation of p53 and induction of tumor cell apoptosis) binds to p53 and induces its accumulation in tumor cells. RITA prevents p53-HDM2 interaction in vitro and in vivo and affects p53 interaction with several negative regulators. It induces expression of p53 target genes and apoptosis in various tumor cell lines expressing wild-type p53.
Peptide sequence
N/A
CAS number
213261-59-7
Molecular weight
292.37
Category
Biochemicals
Other name
5,5'-(2,5-Furandiyl)bis-2-thiophenemethanol; NSC 652287
Molecular formula
C₁₄H₁₂O₃S₂
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>25 mg/ml) or EtOH (>5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
