RKI-1447 for cell activation
Catalog number
2472-25
Name
RKI-1447 for cell activation
Size
25 mg
Price
458.00 EUR
Supplier
Details
Description
A highly potent inhibitor of Rho-associated kinases ROCK1 and ROCK2 (IC₅₀ values: 14.5 nM for ROCK1 and 6.2 nM for ROCK2). RKI-1447 suppresses ROCK-dependent signaling, cell morphology, anchorage-independent cell growth, migration invasion and in vivo growth of mammary tumors.
Peptide sequence
N/A
CAS number
1342278-01-6
Molecular weight
326.37
Category
Biochemicals
Other name
N-[(3-hydroxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl urea
Molecular formula
C₁₆H₁₄N₄O₂S
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>50 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
