PXD101 for cell activation
Catalog number
2480-5
Name
PXD101 for cell activation
Size
5 mg
Price
132.00 EUR
Supplier
Details
Description
A potent histone deacetylase (HDAC) activity inhibitor. It inhibits HDAC activity in HeLa cell extracts with an IC₅₀ of 27 nM. Belinostat significantly increases acetylation of histones H3 and H4 and potently inhibits the growth of prostate cancer cell lines (IC₅₀ range from 0.5 to 2.5 µM) with cytotoxic activity preferentially against tumor cells.
Peptide sequence
N/A
CAS number
414864-00-9
Molecular weight
318.35
Category
Biochemicals
Other name
(E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide; Belinostat
Molecular formula
C₁₅H₁₄N₂O₄S
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>50 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
