Human CellExp™ VSIG4, human recombinant

Catalog number
P1018-10
Name
Human CellExp™ VSIG4, human recombinant
Size
10 µg
Price
208.00 EUR
Supplier

Details

Target
VSIG4
Background
VSIG4 (V-set and immunoglobulin domain containing 4), as known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation.
Concentration
N/A
Molecular weight
68 kDa
Synonym
V-set and immunoglobulin domain containing 4; Z39Ig; CRIg
Other name
V-set and immunoglobulin domain containing 4; Z39Ig; CRIg
NCBI gene number
11326
NCBI gene
VSIG4
Gene source
Human
NCBI number
Q9Y279
Recombinant
Yes
Source
HEK 293 cells
Purification
≥ 98%
Tested applications
SDS-PAGE, N/A
Level of endotoxin
< 0.06 EU/mg
Tested activity
N/A
Biological activity
N/A
Reesults
N/A
Binding ability
N/A
Unit
N/A
Storage condition
-20°C
Shipping under
Gel pack
Physical appearance
Lyophilized
Physical properties
Lyophilized from 0.2μm-filtered solution in PBS.
How to reconstitute
Reconstitute in 1X PBS to the desired protein concentration.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants