Human CellExp™ NOV, human recombinant

Catalog number
P1022-25
Name
Human CellExp™ NOV, human recombinant
Size
25 µg
Price
295.00 EUR
Supplier

Details

Target
NOV
Background
Nephroblastoma Overexpressed Gene Protein (NOV), also known as CCN3, IGFBP9 and NOVH, is one of the CCN family of secreted proteins. It is expressed in bone marrow, thymic cells and nephroblastoma. NOV signals through integrin receptors, NOTCH1 and fibulin 1c to regulate multiple cellular activities, such as cell adhesion, migration, proliferation and differentiation. The reported functions of NOV are diverse. It has been reported to play a role in angiogenesis and stem cell self-renewal. It has also been implicated in osteogenic differentiation, embryo development and cancer pathogenesis.
Concentration
N/A
Molecular weight
20-50 kDa
Synonym
Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH
Other name
Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH
NCBI gene number
4856
NCBI gene
NOV
Gene source
Human
NCBI number
P48745
Recombinant
Yes
Source
CHO cells
Purification
> 95%
Tested applications
SDS-PAGE, HPLC
Level of endotoxin
< 0.2 EU/μg
Tested activity
Prolifiration assay
Biological activity
ED50
Reesults
N/A
Binding ability
N/A
Unit
N/A
Storage condition
-20°C
Shipping under
Gel pack
Physical appearance
Lyophilized
Physical properties
Lyophilized after extensive dialysis against PBS.
How to reconstitute
Reconstituted in ddH2O at 100 μg/mL.
Aa sequence
TQRCPPQCPG RCPATPPTCA PGVRAVLDGC SCCLVCARQR GESCSDLEPC DESSGLYCDR SADPSNQTGI CTAVEGDNCV FDGVIYRSGE KFQPSCKFQC TCRDGQIGCV PRCQLDVLLP EPNCPAPRKV EVPGECCEKW ICGPDEEDSL GGLTLAAYRP EATLGVEVSD SSVNCIEQTT EWTACSKSCG MGFSTRVTNR NRQCEMLKQT RLCMVRPCEQ EPEQPTDKKG KKCLRTKKSL KAIHLQFKNC TSLHTYKPRF CGVCSDGRCC TPHNTKTIQA EFQCSPGQIV KKPVMVIGTC TCHTNCPKNN EAFLQELELK TTRGKM
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants