Ryanodine for cell activation
Catalog number
2489-1000
Name
Ryanodine for cell activation
Size
1 mg
Price
349.00 EUR
Supplier
Details
Description
Ryanodine is a naturally occurring poisonous alkaloid that acts as a potent inhibitor of Ca²⁺ release from sarcoplasmic reticulum (IC₅₀s = 10 and 2.8 nM in skeletal and cardiac muscle, respectively). At micromolar (~100 μM) concentrations, ryanodine irreversibly inhibits ryanodine receptor channel opening, which results in paralysis.
Peptide sequence
N/A
CAS number
15662-33-6
Molecular weight
493.55
Category
Biochemicals
Other name
(3S,4R,4aR,6S,6aS,7S,8R,8aS,8bR,9S,9aS)-dodecahydro-4,6,7,8a,8b,9a-hexahydroxy-3,6a,9-trimethyl-7-(1-methylethyl)-6,9-methanobenzo[1,2]pentaleno[1,6-bc]furan-8-yl ester-1H-pyrrole-2-carboxylic acid
Molecular formula
C₂₅H₃₅NO₉
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
No
Purification
≥98%
Reconstitute instructions
DMSO (>10 mg/ml) or EtOH (~5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
