ML243 for cell activation
Catalog number
2515-5
Name
ML243 for cell activation
Size
5 mg
Price
153.00 EUR
Supplier
Details
Description
ML-243 is a selective inhibitor of cancer stem cells. Displays 32-fold selective inhibition of a breast cancer stem cell-like cell line (EC₅₀ = 2.0 µM) over a control (mammary epithelial) cell line (EC₅₀ = 64 µM). It weakly antagonizes the adenosine A2A receptor (IC₅₀ = 10 µM) and has no effect on 68 other targets commonly used in drug discovery for lead profiling.
Peptide sequence
No
CAS number
1426576-80-8
Molecular weight
260.35
Category
Biochemicals
Other name
(2E)-N-(4,5-dihydro-2-thiazolyl)-3-(4-ethylphenyl)-2-propenamide; CID-50910523
Molecular formula
C₁₄H₁₆N₂OS
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (5 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
