Retro-2 for cell activation
Catalog number
2516-25
Name
Retro-2 for cell activation
Size
25 mg
Price
414.00 EUR
Supplier
Details
Description
An inhibitor of ribosome-inactivating proteins (RIPs). At a concentration of 200 mg/kg, Retro-2 displayed full protection of mice against a dose of ricin that killed 90% of an unprotected control mouse population. Blocks Leishmania parasitophorous vacuole (LPV) development. Retro-2 inhibited the replication of Leishmania parasites in axenic cultures.
Peptide sequence
No
CAS number
1429192-00-6
Molecular weight
320.41
Category
Biochemicals
Other name
Retro-2(cycl); (±)-2-(5-methylthiophen-2-yl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one; Ricin retrograde transport blocker
Molecular formula
C₁₉H₁₆N₂OS
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~5 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Virus
retro
Additional description
For cells, cell lines and tissues in culture till half confluency.
